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Novel and Simple Syntheses of 5H-Pyrido[4, 3-b]indole (γ-Carboline) Derivatives Having a Methoxycarbonyl Group at the 4-Position Based on 1-Hydroxyindole Chemistry

机译：基于1-羟基吲哚化学的4位甲氧基羰基的5H-吡啶并[4,3-b]吲哚（γ-咔啉）衍生物的新颖简单合成

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摘要

A simple synthetic method for 5H-pyrido[4, 3-b]indole (γ-carboline) derivatives having a methoxycarbonyl group at the 4-position was developed based on 1-hydroxyindole chemistry. By applying the method, various 3-substituted metyl 5H-pyrido[4, 3-b]indole-4-carboxylates and 2-substituted methyl 2, 3-dihydro-3-oxo-5H-pyrido[4, 3-b]indole-4-carboxylates were prepared.

机译：基于1-羟基吲哚化学，开发了一种简单的合成方法，用于合成4-位具有甲氧基羰基的5H-吡啶并[4,3-b]吲哚（γ-咔啉）衍生物。通过应用该方法，各种3-取代的甲基5H-吡啶基[4,3-b]吲哚-4-羧酸酯和2-取代的甲基2,3-二氢-3-氧代-5H-吡啶基[4,3-b]制备了吲哚-4-羧酸盐。

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Somei, Masanori; Yamada, Fumio; Yamamura, Gaku;
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年度 1998
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1. Novel and Simple Syntheses of 5H-Pyrido[4,3-b]indole (γ-Carboline) Derivatives Having a Methoxycarbonyl Group at the 4-Position Based on 1-Hydroxyindole Chemistry [J] . Masanori Somei, Fumio Yamada, Gaku Yamamura Chemical and Pharmaceutical Bulletin . 1998,第2期

机译：基于1-羟基吲哚化学的新颖且简单的合成方法，是在4-位具有甲氧羰基的5H-吡啶并[4,3-b]吲哚（γ-咔啉）衍生物
2. Simple Synthesis of 1,3,4,5a,6,10b,11,11a-Octahydro-2H-Pyrazino[1',2':1,5]Pyrrolo[2,3-b]Indole Derivatives Based on 1-Hydroxyindole Chemistry [J] . Yoshikazu Fukui, Masanori Somei Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry . 2001,第11期

机译：基于1-羟基吲哚的1,3,4,5a，6,10b，11,11a-八氢-2H-吡嗪并[1'，2'：1,5]吡咯并[2,3-b]吲哚衍生物的简单合成化学
3. The chemistry of indoles. CIII. Simple syntheses of serotonin, N-methylserotonin, bufotenine, 5-methoxy-N-methyltryptamine, bufobutanoic acid, N-(indol-3-yl)methyl-5-methoxy-N-methyltryptamine, and lespedamine based on 1-hydroxyindole chemistry. [J] . Somei M, Yamada F, Kurauchi T, Chemical and Pharmaceutical Bulletin . 2001,第1期

机译：吲哚的化学。 CIII。基于1-羟基吲哚化学的5-羟色胺，N-甲基5-羟色胺，丁苯丁宁，5-甲氧基-N-甲基色胺，丁苯丁酸，N-（吲哚-3-基）甲基-5-甲氧基-N-甲基色胺和莱斯佩明的简单合成方法。
4. New Development and Requirement of Indole Chemistry-Syntheses of Indolenine Derivatives [C] . International symposium on fine chemistry and functional polymers . 2008

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5. I. Structure-based molecular modeling and synthesis of indole derivatives as non-phenolic analogues of mycophenolic acid. II. 3D-QSAR studies using CoMFA on homotropane and tropane derivatives as dopamine transporter and serotonin transporter ligands. [D] . El-Araby, Moustafa El-Sayed. 2001

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7. The Chemistry of Indoles. XIII. Syntheses of Substituted Indoles carrying an Amino, Nitro, Methoxycarbonyl, or Benzyloxy Group at the 4-Position and Their 1-Hydroxy Derivatives [O] . Somei, Masanori, Inoue, Satomi, Tokutake, Shoichi, 1981

机译：吲哚的化学.XIII。在4-位上带有氨基，硝基，甲氧基羰基或苄氧基的取代吲哚及其1-羟基衍生物的合成
8. Syntheses of Thienylamphetamine Derivatives via Borane Chemistry [R] . Marks, R. C. 1988

机译：通过硼烷化学合成噻吩并苯丙胺衍生物

Novel and Simple Syntheses of 5H-Pyrido[4, 3-b]indole (γ-Carboline) Derivatives Having a Methoxycarbonyl Group at the 4-Position Based on 1-Hydroxyindole Chemistry

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